Defining the attributes of rare CD4 T cells that harbor latent HIV under therapy with anti-retroviral agents has been challenging due to difficulties in identifying and isolating these cells. These ce
HIV-vpr expression was mainly detected in tubule cells after infection. By comparing the HIV-infected and wild type kidney cells on single cell level, a strong shift was observed in the PT S3 segment
The restructuring of chromatin architecture following lentiviral integration is not well elucidated. We jointly interrogate (HIV-distal & -local) chromatin organization (via Hi-C & ATAC-seq) and the R