Striatal MPP⁺ levels.

MPP+ levels were measured in striatal tissues collected from wildtype (WT), uninduced (No dox) and dox-induced (Dox) transgenic mice 90 min post-MPTP injection (30 mg/kg) via HPLC with electrochemical detection. MPP+ was extracted from tissues homogenized in the presence of 0.4N perchloric acid and measured against a known standard. Values are presented as ng MPP+/mg protein , n = 3 per treatment condition.