Supplementary data, code and audit trail for "Efficacy and Safety of Biologic Therapies Targeting Type 2 and Epithelial-Alarmin Pathways in Chronic Obstructive Pulmonary Disease: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials"

Reproducibility materials for a systematic review and network meta-analysis of biologic therapies in COPD. Contains the full search strategy and execution log with per-interface strings, deduplication script and record-level files, record-level screening decisions and reconciliation, the extraction workbook and per-trial provenance records for all 15 trial nodes, the pool/node map, the governed analysis dataset, all analysis and sensitivity scripts with sessionInfo records, fitted model objects, assessor-level risk-of-bias assessments and adjudication record, a kappa recomputation script, and the CINeMA input file. Published trial PDFs are excluded for copyright reasons; source identifiers are given in the manifest so they can be retrieved directly. PROSPERO registration: CRD420261448694