Table_1_Preoperative hemoglobin thresholds for survival equity in women and men.docx

Anemia affects humans throughout life, and is linked to higher morbidity and mortality. Unclear is whether hemoglobin values are equivalent between women and men. This study evaluates the association of preoperative hemoglobin levels with in-hospital mortality and estimates thresholds for survival equity between men and women. All adult patients undergoing surgery between 2010 and 2019 from 14 German hospitals were included in the study. Thresholds for survival equity were determined with generalized additive models. In total, 842,130 patients with a median in-hospital follow-up time of 7 days were analyzed. During follow-up 20,370 deaths occurred. Preoperative hemoglobin stratified in-hospital mortality (log-rank test p

贫血贯穿人类的一生，与其较高的发病率和死亡率密切相关。关于血红蛋白值在男性和女性之间是否等效尚无定论。本研究旨在评估术前血红蛋白水平与住院死亡率之间的关联，并估计男性和女性之间生存均等性的阈值。纳入了2010年至2019年间来自14家德国医院的全部成年手术患者。生存均等性的阈值通过广义加性模型确定。共分析了842,130名患者，其中位住院随访时间为7天。在随访期间，发生了20,370例死亡。术前血红蛋白水平对住院死亡率进行了分层（log-rank检验p值）