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Comparison of gene expression profiles of HIV-specific CD8 T cells from controllers and progressors and Jurkat cells with or without PD-1 ligation

NIAID Data Ecosystem2026-03-10 收录

HIV/SHIV感染免疫应答

PD-1/PD-L1信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE24082 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2017-01-17

癌症免疫耐受

PD-1/PD-L1信号通路

PD-1 ligation delimits immunogenic responses in T cells. However, the consequences of PD-L1 ligation in T cells are uncertain. We found that T cell expression of PD-L1 in cancer was regulated by tumor

NIAID Data Ecosystem110

Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling

免疫调节

PD-1/PD-L1信号通路

The physiological roles of PD-1 signaling in B-cell and antibody (Ab) responses remain unclear. We report B cell-extrinsic and B cell-intrinsic deficits of humoral immunity in patients and mice defici

NIAID Data Ecosystem50

Blockade of PD-1 Signaling Enhances Th2 Cell Responses and Aggravates Liver Immunopathology in Mice with Schistosomiasis japonica

血吸虫病免疫

PD-1/PD-L1信号通路

Background More than 220 million people worldwide are chronically infected with schistosomes, causing severe disease or even death. The major pathological damage occurring in schistosomiasis is attrib

NIAID Data Ecosystem40

Data_Sheet_1_Stimulation of the PD-1 Pathway Decreases Atherosclerotic Lesion Development in Ldlr Deficient Mice.PDF

动脉粥样硬化免疫

PD-1/PD-L1信号通路

Aim: Signaling through the coinhibitory programmed death (PD)-1/PD-L1 pathway regulates T cell responses and can inhibit ongoing immune responses. Inflammation is a key process in the development of a

NIAID Data Ecosystem90

B cell analyses for PD-1- and PD-L1-deficient humans and PD-1 KO mice

细胞功能研究

PD-1/PD-L1信号通路

We tested the hypothesis that PD-1:PD-L1 signaling is essential for optimal B-cell memory and antibody responses by studying the recently described PD-1-deficient (Ogishi et al. Nat. Med. 2021) and PD

NIAID Data Ecosystem40

Comparison of gene expression profiles of HIV-specific CD8 T cells from controllers and progressors and Jurkat cells with or without PD-1 ligation

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