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BB/DD Transcript Ratios of Genes in the Variable Interval 168.1–169.9 Mb.

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aBoldface indicates RefSeq gene; regular type is locally-confirmed, predicted transcript. bExpression profiling was carried out using Affymetrix #430A mouse gene chips. cTen 21-day old DD and BB Lepob/ob 1jc congenic males were analyzed. dRatio is average B/B signal divided by average D/D signal in the organ. eLower line in µ-array box is p-value, 2-sided t-test, comparing each set of 10 BB and 10 DD mice in the same organ. fSamples for qPCR prepared from 5 BB and 5 DD 90-day old Lepob/ob 1jc males on 2 occasions. gRatios represent relative numbers of transcripts (BB/DD). hPrimer-pairs amplify transcripts of Ll isoforms 1, 2, 4, and 5; these comprise >90% of Ll transcripts. iExpression not detected. jNot significant (p>0.05). kInclusive-only transcripts were detected in a cDNA pool that included whole embryos, 1-day old pups, and other tissues, but not in the cDNA pool prepared from diabetes-relevant organs. lProbes for these genes were neither on the Affymetrix #430A nor analyzed by qPCR.

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2008-07-25
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