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Intestinal cGAS-STING-IFN Signaling Promotes Obesity by Downregulating Microbiota-Derived IAA in Male Mice

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Figshare2025-10-04 更新2026-04-28 收录
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The gut constantly interacts to both pathogens and dietary signals, but how it balances immune and metabolic responses remains unclear. Here, we identify intestinal cGAS, a key DNA sensor, as a central regulator linking gut immunity to whole-body metabolism.

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2025-10-04
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