Factor Xa bound to BAY 3389934

Factor Xa bound to BAY 3389934 Descriptor: 2-(1-methylimidazol-2-yl)ethyl (2~{S})-3-[(5-chloranylthiophen-2-yl)carbonylamino]-2-[[2-ethyl-3-[(3~{S})-3-oxidanyl-2-oxidanylidene-pyrrolidin-1-yl]phenyl]sulfonylamino]propanoate, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CALCIUM ION, ... Authors: Beck, H, Schaefer, M, O'Donnell, J.P. Deposit date: 2025-05-16 Release date: 2025-06-18 Last modified: 2025-07-09 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Discovery of BAY 3389934 Hydrochloride: A Potent and Selective Small-Molecule Dual Factor IIa/Xa Inhibitor with Short Half-Life for the Acute Treatment of Sepsis-Induced Coagulopathy. J.Med.Chem., 68, 2025