Nanoparticles dysregulate the human placental sNanoparticles dysregulate the human placental secretome with consequences on angiogenesis and vascularizationecretome with consequences on angiogenesis and vascularization

Secretomics analysis of conditioned media from first trimester/term human placental explant cultures after exposure to SiO2, TiO2 nanoparticles (NPs) (25 μg/mL) or diesel exhaust particles (DEPs, 0.45 μg/mL)using LC-MS/MS based label-free quantification (LFQ) analysis.