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Transcriptome dynamics of hematopoietic stem cell formation revealed using a combinatorial Runx1/Ly6a reporter system

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NIAID Data Ecosystem2026-03-11 收录
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Single cell RNA-Seq time-course analysis revealed that as pre-HSCs mature into fetal liver-stage HSCs they show signs of interferon exposure, multi-lineage differentiation gene expression signatures, and prolonged cell cycle reminiscent of quiescent adult HSCs. Overall design: Investigation of transcriptome dynamics of hematopoietic stem cell formation using a combinatorial Runx1/Ly6a reporter system

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2020-05-20
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