FaceBase Study of Facial Shape in Tanzania: CIDR

The goals of this project are to identify loci that underlie major genetic determinants of orofacial shape, by means of a GWAS in a cohort of normal African children (from Tanzania) from whom we have collected 3D digitized facial morphometric scans, and a subsequent replication study of normal children from the same population. These studies are part of the NIDCR FaceBase initiative (https://www.facebase.org/). In addition to dbGaP, all study genotype and phenotype data (including primary facial scans and landmarks) will be available for data-sharing with qualified investigators via the NIDCR FaceBase Hub (www.facebase.org/), following approval by the NIDCR FaceBase Data Access Committee. ]]> Inclusion: Tanzanian children aged 3-18, major ethic affiliation Bantu at level of all four grandparents Exclusion: Any orofacial defect, any known birth defect, any known relatives with orofacial cleft, any non-Bantu grandparent]]>