IntroductionFolate and one-carbon metabolism are linked to cancer risk through their integral role in DNA synthesis and methylation. Variation in one-carbon metabolism genes, particularly MTHFR, has b
Observed genotype and haplotype frequencies together with respective odds ratios (ORs) and corresponding 95% confidence intervals for Rad51 polymorphisms in breast cancer cases and control subjects.
aModel, statistical model; FEM, fixed effect model; REM, random effect model. bp value for heterogeneity based on Q test; Abbreviations: GS, gallstone; GBC, gallbladder cancer.
Independent GWAS Loci. Table of independent associations with prostate cancer. Index SNPs with are grouped together, and shown with source citations. A locus with a significant number of correlated SN