A Regioselective Approach to Trisubstituted Pyrazoles via Palladium-Catalyzed Oxidative Sonogashira-Carbonylation of Arylhydrazines
收藏NIAID Data Ecosystem2026-03-10 收录
下载链接：
https://figshare.com/articles/dataset/A_Regioselective_Approach_to_Trisubstituted_Pyrazoles_via_Palladium-Catalyzed_Oxidative_Sonogashira-Carbonylation_of_Arylhydrazines/5136337
下载链接
链接失效反馈官方服务：
资源简介：
A palladium-catalyzed
oxidative carbonylation of arylhydrazines
and alkynes with balloon pressure CO/O2 to afford trisubstituted
pyrazoles in a one-pot manner has been developed. The formation of
trisubstituted pyrazoles involves a sequential C–N bond cleavage,
carbonylation, Sonogashira coupling, Michael addition, and intramolecular
condensation cyclization tandem process. An unprecedented oxidative
Sonogashira-carbonylation reaction of arylhydrazine plays a key role
for such a facile approach to pyrazoles.
创建时间：
2017-06-22
