Reactivation of the gammaherpesviruses Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV) and murine gammaherpesvirus 68 (MHV68) from latently infected B cells has been linked to
Although most patients with multiple myeloma respond to treatment initially, therapy resistance develops almost invariably and only a subset of patients show durable responses to immunomodulatory (IMi
The insulin receptor (INSR) has been recently shown to be hyperactive in hepatic stellate cells (HSCs) in human and rodent liver fibrosis. To explore HSC cellular mechanisms that the INSR regulates du
The goals of this study were to identify alterations in the gene expression profile (GEP) of spleen B cells purified from Dock10 knockout (ko) mice [C57BL/6 Dock10tm1a(EUCOMM)Hmgu/Ieg, European Mouse
Cells communicate with their environment via surface proteins and secreted factors. However, how environmental cues modify the extracellular proteome is not known. Unconventional protein secretion (UP
