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Transcriptomics changes in liver metastatic biopsies of colorectal carcinoma between pre-treated and acquired resistance to Cetuximab

NIAID Data Ecosystem2026-03-11 收录

结直肠癌肝转移转录组学

西妥昔单抗耐药机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE84270 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2019-06-20

西妥昔单抗耐药机制

宫颈鳞状细胞癌

Cetuximab (Erbitux) is an antibody drug against EGFR and commonly used in late stage HNSCC and metastatic colorectal cancer. The oncogenic mutation of certain genes are known to drive Cetuximab resist

NIAID Data Ecosystem70

Molecular mechanisms and potential therapeutic drugs linking to cetuximab-resistance reactions in cancer cells

西妥昔单抗耐药机制

宫颈鳞状细胞癌

To obtain differentially expressed genes associated with cetuximab resistance mechanism, we analyzed RNA samples using whole genome microarray expression profiling as a discovery platform to identify

NIAID Data Ecosystem50

Genes expression in the different passages of OECM-1 cell line received cetuximab

西妥昔单抗耐药机制

头颈鳞癌免疫治疗

Recent clinical studies showed those patients who underwent cetuximab treatment before IO therapy seem to be worse. However, the correlation between these therapies is unclear. We aimed to reveal that

NIAID Data Ecosystem40

Whole-transcriptome profilings between a pair of HCA7-derived KRAS-wildtype cetuximab sensitive and resistant colon cancer cells from 3D culture

西妥昔单抗耐药机制

结肠癌转录组分析

We report the results of RNA-Seq and small RNA-Seq from a pair of HCA7-derived, KRAS wildtype CC and CC-CR cultured in 3D. A total of 361 genes showed more than a two-fold change in expression (false-

NIAID Data Ecosystem60

ENU_JHU_029_Cetuximab. ENU_JHU_029_Cetuximab

西妥昔单抗耐药机制

宫颈鳞状细胞癌

Cetuximab is a targeted monoclonal antibody against the epidermal growth factor receptor (EGFR) which is used therapeutically for the treatment of head and neck squamous cell carcinoma (HNSCC). The Ce

NIAID Data Ecosystem50

Transcriptomics changes in liver metastatic biopsies of colorectal carcinoma between pre-treated and acquired resistance to Cetuximab

资源简介：

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