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Crystal structure of human Pim-1 in complex with DAPPA

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of human Pim-1 in complex with DAPPA Descriptor: (2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-yl]phenyl}prop-2-enoic acid, MAGNESIUM ION, Proto-oncogene serine/threonine-protein kinase Pim-1 Authors: Qian, K. Deposit date: 2008-10-29 Release date: 2009-03-10 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode. J.Med.Chem., 52, 2009
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2008-10-29
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