Next Generation Sequencing Facilitates Quantitative Analysis of Healthy Control and Patients of Systematic Lupus Erythematosus Neutrophil Transcriptomes. Next Generation Sequencing Facilitates Quantitative Analysis of Healthy Control and Patients of Systematic Lupus Erythematosus Neutrophil Transcriptomes

We aimed to investigated the molecular mechanism of neutrophil in SLE. We isolated neutrophils from 6 new onset treatment-naïve SLE patients and 6 age/sex-matched HCs and examined the transcriptome by RNA-seq. Overall design: Neutrophil lncRNA and mRNA profiles of healthy control and patients of systematic lupus erythematosus