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Mapping T cell responses to native and neo- islet antigen epitopes in at risk and type 1 diabetes subjects

ChEBI2021-05-29 更新2026-07-12 收录

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-10323 数据链接链接失效反馈

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Mapping T cell responses to native and neo- islet antigen epitopes in at risk and type 1 diabetes subjects

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2021-05-29

自身免疫糖尿病

细胞基因表达

Analyze the effect of TLR9 deficiency on immue cell function at the gene expression level. Our hypothesis was that TLR9 deficiency promotes CD73 expression in T cells thus regulates autoimmune diabete

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Single cell analysis of CD1a-restricted Group A streptococcus (GAS)-reactive peripheral and cutaneous T cells. Single cell analysis of CD1a-restricted Group A streptococcus (GAS)-reactive peripheral and cutaneous T cells

单细胞免疫组学

T细胞抗原应答

Skin and blood single cell RNA sequencing datasets of IL-22- and IFNγ-secreting CD1a-reactive GAS-responsive T cells were generated from four healthy skins, five healthy PBMCs and three psoriatic PBMC

NIAID Data Ecosystem40

Analysis of gene expression in pancreatic beta-cells of NOD mice

糖尿病β细胞转录组

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Pancreatic beta-cells were purified by FluoZin-3-AM and TMRE from at least eight mice to minimize the individual heterogeneity on diabetes progression, and devoted to transcriptome analysis. 6-week-ol

NIAID Data Ecosystem30

Reduced Type I Interferon response signature detected in dendritic cells from prediabetic NOD mice compared to C57BL/6.g7 and Rag KO.

自身免疫糖尿病

树突状细胞

Investigating type I interferon in prediabetic stage of DCs from NOD mice compared to C57BL/6.g7 and Rag KO mice. Overall design: RNAseq was used to study splenic cDC1, cDC2, pDC, moDC, and monocyte p

NIAID Data Ecosystem40

The lack of consensus for I-A(g7)-peptide binding motifs: Is there a requirement for anchor amino acid side chains?

MHC-肽结合基序

自身免疫糖尿病

We discuss here the problems in identifying sequence motifs of peptides that bind to I-A(g7), the class II histocompatibility molecule of NOD diabetic mice. We present studies that indicate a minor co

PubMed Central1999-07-20 更新40

Mapping T cell responses to native and neo- islet antigen epitopes in at risk and type 1 diabetes subjects

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