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Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells. Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells

NIAID Data Ecosystem2026-03-13 收录

胰腺β细胞

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数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA857289 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2022-07-09

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ChIP-seq表观遗传学

Mammalian genomes contain several billion base pairs of DNA which are packaged in chromatin fibers. At selected gene loci, cohesin complexes have been proposed to arrange chromatin fibers into higher-

NIAID Data Ecosystem80

The Dlk1-Dio3 noncoding RNA cluster coordinately regulates mitochondrial respiration and chromatin structure to establish proper cell state for muscle differentiation. The Dlk1-Dio3 noncoding RNA cluster coordinately regulates mitochondrial respiration and chromatin structure to establish proper cell state for muscle differentiation

肌肉分化分子机制

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To investigate the collective role of the Dlk1-Dio3 ncRNA cluster in myogenesis, we developed two stable CRISPR-Cas9 gene-edited C2C12 skeletal muscle cell lines, Meg3-proximal cis-acting sequence (Me

NIAID Data Ecosystem70

Neurospora crassa Gene Expression Profiling - FGSC 11156-2 transcriptome. Neurospora crassa strain:FGSC 11156 | isolate:FGSC 11156

基因表达谱分析

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Neurospora crassa Chromatin Regulatory Network Gene Expression Profiling. Sample from cells grown at 30C in full light with shaking for 24 hours

NIAID Data Ecosystem70

The RNA N6-methyladenosine regulates chromatin remodeling and transcription [seq_mettl3ChIP]. The RNA N6-methyladenosine regulates chromatin remodeling and transcription [seq_mettl3ChIP]

表观转录组学

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The N6-methyladenosine (m6A) has been shown to regulate stability and translation of messenger RNA (mRNA) in various biological processes. Here, we show that the knockout of the m6A writer Mettl3 or a

NIAID Data Ecosystem80

Additional file 6 of G-quadruplexes are transcription factor binding hubs in human chromatin

G-四链体功能

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Additional file 6: Table S5. Randomization of predicted consensus dsDNA binding sites (from JASPAR) or endogenous G4s in promoters / open chromatin promoters. Enrichment at TF chromatin binding sites

NIAID Data Ecosystem70

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells. Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells

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