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Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (local refinement)

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Protein Data Bank Japan2025-06-25 更新2026-03-21 收录
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Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (local refinement) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... Authors: Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. Deposit date: 2022-06-27 Release date: 2022-08-31 Last modified: 2025-06-25 Method: ELECTRON MICROSCOPY (3.11 Å) Cite: Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13, 2022
创建时间:
2022-06-27
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