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Engineered antibodies to control flexibility.

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DataCite Commons2026-04-02 更新2026-05-03 收录
下载链接:
https://doi.esrf.fr/10.15151/ESRF-ES-2394596062
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资源简介:
Antibodies can be engineered to reduce their flexibility, using a range of technologies including disulfide engineering and interface manipulation. We have previously demonstrated that antibody flexibility is directly linked to activity. Under this proposal, we will assess the flexibility in solution of a series of antibodies to which both disulfide and interface engineering has been applied.
提供机构:
European Synchrotron Radiation Facility
创建时间:
2026-04-02
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