Targeted Cortical Reorganization using Optogenetics in Non-human primates: Electrocorticography in Sensorimotor Cortex during Optogenetic Stimulation
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https://datadryad.org/dataset/doi:10.7272/Q61834NF
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资源简介:
The data consists of electrocorticography (ECoG) recordings over primary
somatosensory and primary motor cortices in two rhesus macaques that
expressed C1V1 optogenetic channels in pyramidal neurons. The experimental
setup, including the optogenetic expression and simultaneous ECoG and
laser stimulation, are detailed in (Yazdan-Shahmorad et al., 2016).
This dataset was collected during a series of ~1.5hr long
experiments in which laser pulse trains were used to repeatedly stimulate
one or two cortical sites. Each experiment was organized into blocks:
Recording Blocks: Passive recordings were conducted during spontaneous
activity (30 s or 5 min) Testing Blocks: 100 laser pulses were delivered
with each laser, each in separate, interleaved blocks (10 pulses, 5ms @ 5
or 7Hz). ECoG signals were recorded simultaneously. Conditioning Blocks:
Laser pulses were delivered through each laser (5ms pulses @ 5 or 7Hz) for
10min. The second laser had a fixed delay relative to the first laser and
this delay varied across experiments. ECoG signals were recorded
simultaneously. A single experiment consisted of a pre-test period, with a
Recording Block (RB) and a Testing Block (TB), followed by 5 repetitions
of a Conditioning Block (CB), RB, and TB, for a total of 6 TB and RB and 5
CB: { RB TB - CB RB TB - CB RB TB - CB RB TB - CB RB TB - CB RB TB }
Reference: YAZDAN-SHAHMORAD, A., DIAZ-BOTIA, C., HANSON, T. L.,
KHARAZIA, V., LEDOCHOWITSCH, P., MAHARBIZ, M. M. & SABES, P. N.
2016. A Large-Scale Interface for Optogenetic Stimulation and Recording in
Nonhuman Primates. Neuron, 89, 927-39.
提供机构:
Dryad
创建时间:
2018-05-16



