The S. cerevisiae methyltransferome.

MTases are grouped according to the structural similarity of their catalytic domains (Fold) and substrate specificity (Substrate). Known MTases with experimentally determined substrate specificity are shown in regular font, putative MTases are italicized, and the newly detected MTase is highlighted in bold. Non-periodic MTases are underlined. With the exception of aDNA, containing 6-O-methylguanine, b5-methyltetrahydropteroyltri-L-glutamate, and c5,10-methylenetetrahydrofolate, AdoMet is the methyl group donor.