Evaluation of the safety of the dynamic algorithm <i>vs</i> the static protocol according to patients’ profile (vigorous <i>vs</i> frail patients).

p1 represents the statistical analysis between frail and vigorous patients treated with the static protocol; p2 represents the statistical analysis between frail and vigorous patients treated with the dynamic algorithm; p3 represents the statistical analysis between frail patients treated with the static protocol and the dynamic algorithm; p4 represents the statistical analysis between vigorous patients treated with the static protocol and the dynamic algorithm. Mild hypoglycemia is defined by a BG level <70 mg/dl (<3.9 mmol/l) in vigorous patients and <100 mg/dl (<5.5 mmol/l) frail patients. Marked hypoglycemia is defined by a BG level <50 mg/dl (<2.8 mmol/l) in vigorous patients and <70 mg/dl (<3.9 mmol/l) frail patients. Hyperglycemia after achieving the target is defined by BG>250 mg/dl (>13.9 mmol/l). (…) represents the % value over all BG measurements.