Effects of LPS treatment on microglia

Microglia, the most abundant type of brain-resident immune cells, continuously surveil the environment and play a central role in shaping the inflammatory state of the central nerve system (CNS). To explore the mechaniam underlying microglial inflammation, we explored the effects of LPS treatment on microglia using RNA-seq. Overall design: In order to identify the key regulators involved in mediating microglial activation and inflammation, we conducted RNA-seq analyses in LPS-stimulated BV2 cells