MOSTWAS models, TWAS summary statistics, and simulation results for Bhattacharya and Love, 2020

This compressed folder contains three sub-folders that all pertain to models and results generated with Multi-Omic Strategies for Transcriptome-Wide Association Studies (MOSTWAS):

MOSTWAS_Models contains compressed folders for MOSTWAS models trains on TCGA breast cancer and ROS/MAP pre-frontal cortex multi-omic data.

Simulations contains Simulation_Results_MOSTWAS.xlsx that provides full simulation results outlined in Bhattacharya and Love, 2020 (paper accompanying MOSTWAS).

TWAS_associations contains four Excel files that provide MOSTWAS and local-only TWAS associations for breast cancer-specific survival (using iCOGs GWAS summary statistics), late-onset Alzheimer's disease risk (using IGAP GWAS summary statistics), and major depressive disorder risk (using PGC GWAS and UK Biobank GWAX summary statistics).