Flavobacterium columnare mRNA sequencing

To compare the transcriptomic profiles of Flavobacterium columnare under two distinct colony morphologies: the smooth colony morphology induced by prolonged starvation and the original rhizoid morphology. By analyzing differential gene expression between these phenotypes, we seek to identify key metabolic pathways, stress-response mechanisms under nutrient-limited conditions. These results could aid in developing targeted interventions strategies to disrupt these adaptive mechanisms, potentially reducing the bacterium's capacity for nutrient deprivation tolerance in the natural environment.