Radioligand binding studies were carried out as described under “Materials and Methods”. The half-maximal inhibitory concentrations (IC50) for competition binding assays were analyzed by nonlinear reg
We have identified 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin ([3H]7-OH-DPAT) as a selective probe for the recently cloned dopamine D3 receptor and used it to assess the presence of this receptor a