Regulation of liver regeneration by interference with TNF alpha mediated inflammation
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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The study examined the role of TNF alpha in regulation of liver regeneration. For this purpose animals were divided in three groups of healthy controls, 2/3 partial hepatectomy alone, and animals pretreated with TNF alpha antagonist followed by 2/3 partial hepatectomy.Liver regeneration responses were then examined in conjunction with gene expression analysis at the peak of partial hepatectomy induced DNA synthesis. Substantive differences were identified in multiple gene ontology groups and cellular events and processes to indicate that TNF alpha was deleterious for partial hepatectomy induced liver regeneration.
提供机构：
Albert Einstein College of Medicine
创建时间：
2022-02-20
