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Crystal structure of CMET in complex with a novel inhibitor

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Protein Data Bank Japan2023-11-29 更新2026-05-23 收录
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Crystal structure of CMET in complex with a novel inhibitor Descriptor: Hepatocyte growth factor receptor, ~{N}1'-[3-fluoranyl-4-(10~{H}-pyrido[3,2-b][1,4]benzoxazin-4-yloxy)phenyl]-~{N}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Authors: Su, H.X, Liu, Q.F, Chen, T.T, Li, M.J, Xu, Y.C. Deposit date: 2021-08-11 Release date: 2022-08-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase J.Med.Chem., 66, 2023

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2021-08-11
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