Structure of KHK in complex with compound 3
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Structure of KHK in complex with compound 3 Descriptor: 6-[(3~{R},4~{S})-3,4-bis(oxidanyl)pyrrolidin-1-yl]-2-[(2~{S},3~{R})-2-methyl-3-oxidanyl-azetidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile, Ketohexokinase, SULFATE ION Authors: Jasti, J. Deposit date: 2020-03-03 Release date: 2020-09-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose. J.Med.Chem., 63, 2020
创建时间：
2020-03-03
