Translational regulation of RANKL by CPEB2 regulates mammary gland development and luminal tumorigenesis (RIP-seq)

Here we show that the RNA-binding protein CPEB2 controls synthesis of RANKL, thereby modulating epithealial proliferation, differentiation and breast cancer outcome Overall design: RNA-immunoprecipitation sequencing of CPEB2-associated mRNAs in WT and CPEB2-KO mammary epithelial cells