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ITK kinase domain in complex with inhibitor compound

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4qd6
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ITK kinase domain in complex with inhibitor compound Descriptor: Tyrosine-protein kinase ITK/TSK, trans-4-({6-[(5-phenyl-1H-pyrazol-3-yl)amino]-4-(phenylsulfonyl)pyridin-2-yl}amino)cyclohexanol Authors: McEwan, P.A, Barker, J.J, Eigenbrot, C. Deposit date: 2014-05-13 Release date: 2015-01-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Design, synthesis and structure-activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK). Bioorg.Med.Chem.Lett., 24, 2014
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2014-05-13
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