Antibiotic resistance and resistant genes in Escherichia coli from human, poultry and environmental samples in urban and rural Bangladesh (2017-18)

The dataset includes information on antibiotic-resistance and resistance genes in bacteria (Escherichia coli) from humans, poultry and the environment in rural households, poultry farms and urban food markets. The rural households and poultry farms (broiler chickens) were located in Mirzapur, Tangail district; and urban food markets were located in Dhaka city, Bangladesh. Environmental samples were collected from surface water, water supply, wastewater, soil, animal faeces (poultry and cattle) and solid waste between February 2017 and October 2018 . DNA samples from antibiotic-resistant bacteria found in all samples were analysed for quantitative assessment of two resistance genes. Trained staff from the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) undertook sample collection and laboratory analysis. The aim of the study was to assess the prevalence and abundance of antibiotic-resistant bacteria and associated genes among humans, poultry and environmental compartments in Bangladesh. The survey was part of a wider research project, Spatial and Temporal Dynamics of Antimicrobial Resistance Transmission from the Outdoor Environment to Humans in Urban and Rural Bangladesh. The research was funded by NERC/BBSRC/MRC on behalf of the Antimicrobial Resistance Cross-Council Initiative award NE/N019555/1. Full details about this dataset can be found at https://doi.org/10.5285/0239cdaf-deab-4151-8f68-715063eaea45

本数据集收录了来自人类、家禽以及乡村家庭、家禽养殖场和城市食品市场的细菌（大肠杆菌）耐药性和耐药基因信息。研究地点包括孟加拉国坦盖尔的米尔扎普尔乡村家庭及家禽养殖场（肉鸡养殖），以及达卡城市的城市食品市场。在2017年2月至2018年10月期间，从地表水、供水、废水、土壤、动物粪便（家禽和牛）及固体废物中收集了环境样本。对从所有样本中发现的抗生素耐药细菌的DNA样本进行了分析，以进行两种耐药基因的定量评估。来自孟加拉国国际腹泻疾病研究中心（icddr,b）的培训人员负责样本收集和实验室分析。本研究旨在评估孟加拉国人类、家禽和环境领域抗生素耐药细菌及其相关基因的流行率和丰度。此次调查是更大规模研究项目的一部分，即《孟加拉国城乡户外环境至人类抗菌素耐药性传播的空间和时间动态》。该研究由NERC/BBSRC/MRC代表抗菌素耐药性跨委员会倡议奖NE/N019555/1资助。关于此数据集的详细信息，请参阅https://doi.org/10.5285/0239cdaf-deab-4151-8f68-715063eaea45。