Transcriptional profiling of human pancreatic tumor cells under nutrient and oxygen deprivation condition

Transcriptional profiling showed that adaptation to nutrient and oxygen deprivation condition is associated with widespread transcriptional reprogramming resulting in the induction of glycolysis and autophagy and repression of the TCA cycle and biosynthesis Human pancreatic tumor cells were cultured in nutrient and oxygen deprivaiton medium for 2 days and 14 days and then were collected for RNAseq.