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Complex of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant with AGI-6780 Inhibitor

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4ja8
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资源简介:
Complex of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant with AGI-6780 Inhibitor Descriptor: 1-[5-(cyclopropylsulfamoyl)-2-thiophen-3-yl-phenyl]-3-[3-(trifluoromethyl)phenyl]urea, CALCIUM ION, GLYCEROL, ... Authors: Wei, W, Chen, L, Wu, M, Jiang, F, Travins, J, Qian, K, DeLaBarre, B. Deposit date: 2013-02-18 Release date: 2013-04-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science, 340, 2013
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2013-02-18
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