Asymmetric Total Synthesis of (−)-Linderol A
收藏Figshare2007-07-20 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Asymmetric_Total_Synthesis_of_-Linderol_A/12063918
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资源简介：
The first asymmetric total synthesis of (−)-Linderol A, a potent inhibitor of melanin biosynthesis of cultured B-16 melanoma cells, has been achieved via two key reactions: a diastereoselective [2+2] photocycloaddition of a coumarin-3-carboxylate bearing a chiral auxiliary with 3-methyl-1-butene and a subsequent stereoconvergent transformation of the photoadducts with use of dimethylsulfoxonium methylide to afford a tetrahydrodibenzofuran derivative.
创建时间：
2007-07-20
