Expression data of HepG2C3A treated by acetaminophen during 72 hours. Homo sapiens

Evaluation of acetaminophen treatment on Hepatic cell line cultivated in conventionnal method and in a new cell culture device (microfluidic biochip) The aim of this study is to understand the transcriptomic responses of cells cultivated in a microsystem by comparison to conventionnal culture method. As a pharmacological example, we choose to used a well known hepatotoxicant : acetaminophen to illustrate the potential of our microsystem. Overall design: 12 samples were analysed corresponding of 4 conditions : 3 replicates cell control in microsystem, 3 replicates cell treated in microsystem, 3 replicates cell control in Petri, 3 replicates cell treated in Petri cultivated during 96 hours including 72 hours of treatment