FGFR1c and Klotho ligand binding and activation
收藏reactome.org2025-01-15 收录
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资源简介：
FGF23 is a member of the endocrine subfamily of FGFs. It is produced in bone tissue and regulates kidney functions. Klotho is essential for endogenous FGF23 function as it converts FGFR1c into a specific FGF23 receptor.
FGF23属于FGFs内分泌亚家族，由骨骼组织产生，并调节肾脏功能。Klotho对于内源性FGF23功能的发挥至关重要，因为它将FGFR1c转化为特定的FGF23受体。
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