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SIRT7 Antagonizes TGF-ß Signaling and Inhibits Breast Cancer Metastasis

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NIAID Data Ecosystem2026-04-29 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP108472
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Protein deacetylase SIRT7 is significantly downregulated in lung metastases of human patient and mouse tissues, and predicted metastasis-free survival. To explore the roles of SIRT7 in breast cancer, we analysed the gene expressions in breast cancer BT549 cells with SIRT7 knockdown or not. Overall design: The mRNA profiles of breast cancer BT549 cells with SIRT7 knockdown or not were generated by deep sequencing using Illumina HiSeq-2000
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2021-09-30
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