Heme NO interaction in Nitrophorin from the European bedbug Cimex lectularius

The signalling molecule nitric oxide (NO) forms reversable bonds with the heme unit of nitrophorins. We suggest to perform Nuclear Inelastic Scattering experiments with very high resolution on the nitrophorin from the European bedbug Cimex lectularius in order to clarify the mechanism of stabilisation of Fe-NO via heme protonation.