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Single-nucleus transcriptomics of Parp7-/- lung

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP678258
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To explore the cell type-specific effects of PARP7 deficiency in the lung, we performed single-nucleus RNA sequencing (snRNA-seq) of lung from WT and Parp7-/- lung. Overall design: 10-month-old wild-type and Parp7-/- mice (2 mice/genotype) were euthanized and lung were collected and snap frozen in liquid nitrogen. Nuclei were isolated from frozen lung and droplet-based snRNA-sequencing was performed using 10x Genomics.
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2026-02-26
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