Engineered variant of I-OnuI meganuclease targeting the HIV CCR5 gene; harbors 43 point mutations relative to wild-type I-OnuI

Protein Data Bank Japan2024-03-06 更新2026-03-21 收录

HIVCCR5基因编辑

核酸酶蛋白质工程

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资源简介：

Engineered variant of I-OnuI meganuclease targeting the HIV CCR5 gene; harbors 43 point mutations relative to wild-type I-OnuI Descriptor: CALCIUM ION, DNA (29-MER), GLYCEROL, ... Authors: Hallinan, J.P, Stoddard, B.L. Deposit date: 2016-09-29 Release date: 2017-05-03 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.106 Å) Cite: The structural basis of altered gene specificity resulting from meganuclease and MegaTAL engineering to be published

创建时间：

2016-09-29

Engineered variant of I-OnuI meganuclease targeting the HIV CCR5 gene; harbors 43 point mutations relative to wild-type I-OnuI

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