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<i>N</i>-Bromosuccinimide Promoted One-Pot Synthesis of Guanidine: Scope and Mechanism

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NIAID Data Ecosystem2026-03-09 收录
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A novel electrophilic one-pot guanidine synthesis has been developed using an olefin, a cyanimide, an amine, and N-bromosuccinimide. A number of guanidine derivatives were prepared with good to excellent yields. An rTRTVI precursor was also prepared based on this useful process.

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2016-02-22
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