PeptideAtlas

PeptideAtlas is a multi-organism, publicly accessible compendium of peptides identified in a
large set of tandem mass spectrometry proteomics experiments. Mass spectrometer output files are
collected for human, mouse, yeast, and several other organisms, and searched using the latest search
engines and protein sequences. All results of sequence and spectral library searching are subsequently
processed through the  Trans
Proteomic Pipeline to derive a probability of correct identification for all results in a
uniform manner to insure a high quality database, along with false discovery rates at the whole atlas
level. Results may be queried and browsed at the PeptideAtlas web site. The raw data, search results,
and full builds can also be downloaded for other uses.

肽Atlas（PeptideAtlas）是一款跨物种、可公开访问的肽段汇编数据库，收录了大规模串联质谱蛋白质组学实验中鉴定得到的肽段。该库收集了人类、小鼠、酵母及其他多个物种的质谱仪输出文件，并采用最新搜索引擎与蛋白质序列进行检索分析。所有序列与谱图库检索得到的结果随后将通过翻译蛋白质组学流程（Trans Proteomic Pipeline）进行统一处理，以标准化方式为所有结果计算正确鉴定的概率，从而保障数据库的高质量，同时计算整个肽Atlas数据库层面的假发现率。用户可通过PeptideAtlas官方网站对检索结果进行查询与浏览。原始数据、检索结果以及完整数据集构建版本亦可下载用于其他研究用途。

搜集汇总

背景与挑战

背景概述

PeptideAtlas是一个多生物体的公开肽数据库，基于大量串联质谱蛋白质组学实验数据构建，涵盖人类、小鼠、酵母等多种生物。数据经过统一处理以确保高质量，支持在线查询和原始数据下载，适用于蛋白质和肽相关研究。