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Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, huwentoxin-IV and saxitoxin (S6IV pi helix conformer)

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Protein Data Bank Japan2024-11-13 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7w9p
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资源简介:
Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, huwentoxin-IV and saxitoxin (S6IV pi helix conformer) Descriptor: (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... Authors: Yan, N, Huang, G, Liu, D, Wei, P, Shen, H. Deposit date: 2021-12-10 Release date: 2022-05-25 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV. Cell Rep, 39, 2022
创建时间:
2021-12-10
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