Comparison of gene expression profile in E. coli BW25113 wild type and ldhA-pflB- double mutant growing microaerobically in M9 media containing 10 g/L Glucose Overall design: two samples: wild type an
Organisms cope with physiological stressors through acclimatizing mechanisms in the short-term, and through adaptive mechanisms over evolutionary timescales. Whereas the former offer a consistent and
We evolved the recoded "amberless" E. coli that is used for incorporating nonstandard amino acids at the TAG codon in the laboratory. We observed parallel mutations in folA (dihydrofolate reductase) t
