Cocrystal of BRD4(D1) with a selective inhibitor
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Cocrystal of BRD4(D1) with a selective inhibitor Descriptor: 1,2-ETHANEDIOL, 4-(1-{1-[2-(dimethylamino)ethyl]piperidin-4-yl}-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-5-yl)-N-(3,5-dimethylphenyl)pyrimidin-2-amine, Bromodomain-containing protein 4 Authors: Johnson, J.A, Cui, H, Shi, K, Aihara, H, Pomerantz, W.C.K. Deposit date: 2020-04-06 Release date: 2020-10-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Selective N-Terminal BET Bromodomain Inhibitors by Targeting Non-Conserved Residues and Structured Water Displacement*. Angew.Chem.Int.Ed.Engl., 60, 2021
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2020-04-06
