Supplementary Material for: Choroidal Metastasis of a Cutaneous Melanoma – A Case Report

Introduction: We report the clinical, imaging, histopathological, and genetic features of a choroidal metastasis originating from a cutaneous melanoma.
Case Presentation: A 92-year-old woman presented with an asymptomatic pigmented lesion in her right eye. She had a history of prior cutaneous melanoma. Work-up revealed widespread metastases to the liver, lungs and brain. Histopathology (post-mortem eye) showed melanoma cells of epithelioid cell type. Genetic analysis was positive for the BRAF V600K variant, confirming the cutaneous origin of the choroidal tumour.
Conclusion: Choroidal metastasis of a cutaneous melanoma is a rare manifestation that can be mistaken for a primary choroidal melanoma. A comprehensive clinical history, histopathology and genetic analysis are useful in distinguishing between the two entities.