Targetting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo [2,3-d] pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization
收藏Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/4fcp
下载链接
链接失效反馈官方服务：
资源简介：
Targetting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo [2,3-d] pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization Descriptor: Heat shock protein HSP 90-alpha, N,N-dimethyl-7H-purin-6-amine Authors: Davies, N.G.M, Browne, H, Davies, B, Foloppe, N, Geoffrey, S, Gibbons, B, Hart, T, Drysdale, M, Mansell, H, Massey, A, Matassova, N, Moore, J.D, Murray, J, Pratt, R, Ray, S, Roughley, S.D, Jensen, M.R, Schoepfer, J, Scriven, K, Simmonite, H, Stokes, S, Surgenor, A, Webb, P, Wright, L, Brough, P. Deposit date: 2012-05-25 Release date: 2012-10-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. Bioorg.Med.Chem., 20, 2012
创建时间：
2012-05-25
